A question posed to Jennifer Aniston by a young fan moved the Hollywood A-lister to tears at Italy's Giffoni Film Festival.

Children from all over the world were invited to the Q&A session with the Friends star, with one girl asking the star, "Have you ever woken up in the morning and not known who you are?"

With her voice breaking, the 47-year-old answers: "That moment has happened to me ... on like ... I can't even ... there's not enough fingers and toes in this entire room to count how many times that moment has happened."

(credit: youtube/dheldevil88816)

The honest answer was met with a flood of applause and Aniston shook her head and dried her eyes with a tissue as she reflected on her emotional response.

The Horrible Bosses star recently wrote an openly letter about body shaming following numerous articles in tabloid magazines and newspapers speculating that she was pregnant.

"I think we need to empower women to not just be about dresses and beauty and selfies, we need to start having conversations and put our phones down and take social media breaks," she told the young audience.