Ross Ford to earn 100th Scotland cap against Australia
Youngster Allan Dell set for debut while Warriors prop Zander Fagerson makes his second appearance.
Edinburgh prop Ross Ford will win his 100th cap for Scotland against Australia on Saturday while club teammate Allan Dell makes his international bow.
The front row will be completed by Glasgow Warriors youngster Zander Fagerson, making his second appearance in a Scotland shirt since his debut in February.
Ford will lead his side in the scrum and head coach Vern Cotter was quick to sing his praises.
"He's been a standout performer for Scotland for those years," he said.
"His experience will be vital with the front row that's going out there with him.
"It's nice to see an old head like that playing his 100th game and he's putting his arms around one guy that's playing his first and the other one just his second."
He added: "That's what the game is about, bringing these people together in the game and it's nice, you've got the two brothers in behind so everybody is aware of it.
"Everybody wants Fordy to have a good game, a memorable game for his 100th, and there's a lot of determination among the group to do well, for him, for everybody.
"I think one of the key themes will be just looking out for each other - looking out for a guy having 100 games, look out for the guy having his first game.
Ford made his bow for Scotland in the Autumn Tests in 2004 and did not don the shirt for his country again until the 2006 Six Nations where he featured against Wales.
Since then Ford has established himself as the first choice hooker and will join Chris Paterson and Sean Lamont in the 100 club when Scotland take on the Wallabies at Murrayfield on Saturday.
Reflecting on the magnitude of his achievement Ford said: "It's a massive honour.
"Obviously there's Mossy [Christ Paterson] and Sean [Lamont] have gone before you and got that milestone, but to be the first forward to that point and be able to represent my country on so many occasions has been a great experience
"Hopefully it will continue for a while longer yet.
"I work hard for what I do and I've enjoyed every cap I've got in and I'm just looking forward to it and excited for the game on Saturday."
Vern Cotter's side take on Australia at Murrayfield on Saturday in the first of three Autumn Test fixtures, with kick-off at 2.30pm.